Discussions tagged “Imiquimod”

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Imiquimod 3.75% Cream: My experience with side effects and what I wish I'd known

I've been using Imiquimod 3.75% Cream for a few weeks now to treat actinic keratosis, and I must say, it's been quite an experience. The cream is supposed to boost your local immune response to fight off those rough, scaly patches, but wow, the side effects can be intense. I've had everything from mild redness and itching to some pretty severe reactions like burning and oozing. I actually had to take a break from using it because it got so bad, but my doctor said it's fairly common. I've also been feeling a bit weak and feverish, but I guess that's just the flu-like symptoms kicking in. I wish I'd known more about these potential side effects before I started. Anyone else have a similar experience? I could really use some tips on managing these side effects better. Also, do any of you know if the skin discoloration is permanent?

SkinCare
MedicalAdvice
Imiquimod
olivia_quinn · 4/18/2026
5 201
1 min read
last active 4/18/2026
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