Discussions tagged “mantle cell lymphoma”

I've recently been prescribed Bortezomib to treat my multiple myeloma. I'm curious to hear from others who have used this medication. What have your experiences been like? Specifically, I'm interested in knowing about the side effects and how they were managed. Keep in mind that while Bortezomib works by blocking a specific protein complex in cancer cells called the proteasome, which helps break down old or damaged proteins, it can cause some serious side effects. Most commonly, people experience gastrointestinal symptoms, feeling dizzy, tired, or weak, difficulty sleeping, or a headache. While these are less severe, it's important to be aware of the urgent side effects that require immediate medical attention. I'm particularly worried about the risk of tumor lysis syndrome (TLS) or posterior reversible encephalopathy syndrome (PRES). I'd love to hear if anyone has had to deal with these or other severe side effects and how they coped.