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billy_cook2026-04-18

I'm looking for some real-world experiences with using Naloxone 0.4mg/ml Injectable in a 1ml syringe. I've read about the side effects (both urgent and common) and want to know what to expect. Can anyone share their experiences with administering this or if side effects were common? I want to be prepared. Loved ones around me have struggled with opioid addiction. Having that fear of potential overdoses is a constant worry. Thank you and stay safe.

1 min read
last active 4/18/2026
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Comments (10)

J
joyce_murray4/15/2026

Just a quick question, does the naloxone have to be injected or can it be administered some other way?

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joshua_morgan4/15/2026

I've had to use it once. It was scary, but it worked. The person was breathing again within minutes. But yeah, the side effects list is daunting.

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richard_wagner4/15/2026

Might not be the most helpful comment, but it scares me that this needs to be discussed so much. Hope everyone is staying safe.

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linda_fernandez4/16/2026

I administered it to my son and he had a hard time breathing afterwards. Be prepared for the fact that you need to monitor him and be ready to do CPR. Obviously, I called 911 right away. 1-800-332-1088 is a good number to call in case of side effects. Just be ready and calm as much as possible, because you are dealing with a life-threatening situation.

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robert_stephens4/16/2026

The training to administer naloxone is essential. It's not just about giving the shot, you have to know what to do when the person wakes up. Everyone is different, but the most important thing is to stay calm and call 911 right away.

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pamela_nelson4/16/2026

I worry about the untrained person administering it. Call 911. Be sure to know how much naloxone you are giving out so that you can explain to the medical personnel. But yeah, it's a lifesaver if used correctly.

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jean_hudson4/16/2026

The bad news: Naloxone doesn’t mean the worst has passed. A person who has received naloxone should be monitored for possible relapse into a coma. The good news: Naloxone can be life-saving. Just be prepared.

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kyle_palmer4/16/2026

Naloxone can be administered into a muscle, under the skin, or in a vein. Know what you are doing.

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patrick_dunn4/16/2026

One time, a friend of mine was in and out. I administered Naloxone 0.4mg/ml Inj. We were freaking out. All those severe side effects you mentioned were listed in the info with the Naloxone, right? The person had chest pain or pressure, but even though I worried about that, it was the only side effect. Don't forget, even if naloxone gets the job done, it's also temporary. Emergency medical help is still needed.

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nancy_santos4/16/2026

I've seen it used multiple times in my job as a paramedic. It's amazing how fast it works, but every time it's a mix of relief and anxiety. The relief is they're breathing again but anxiety because of the side effects you mentioned. The oddest side effect I've seen was some hallucinations. Be ready to respond to any scary side effects.