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kenneth_jordan2026-04-17

I've been prescribed Avalide 300-12.5 Tablets for my high blood pressure, and I'm a bit concerned about the possible side effects. The medication combines irbesartan and hydrochlorothiazide, both of which have potential serious side effects. I've read that symptoms like severe allergic reactions, changes in eyesight, kidney issues, and even skin cancer are possible. Has anyone else experienced these side effects? I'm also curious about the less severe but still important side effects, like feeling dizzy or weak. How common are these? Anyone have any tips on managing them?

1 min read
last active 4/17/2026
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Comments (5)

J
jean_hudson4/17/2026

Seriously, if you experience any severe symptoms, don’t wait it out. I put off calling my doctor and ended up in the ER. It was scary, but I’m okay now. Just go to the doctor as soon as you feel something’s wrong.

R
ronald_pierce4/17/2026

Did you know that Avalide can cause changes in blood sugar levels? It's not just about the blood pressure, so keep an eye on that too.

F
frank_vargas4/17/2026

I’d be careful about the electrolyte imbalance. I’ve seen it happen with other diuretics, and it can be pretty serious. Make sure you’re getting regular check-ups and monitoring your electrolytes.

L
larry_gardner4/17/2026

I think the risk of skin cancer is a bit overblown. I’ve been on it for years and haven’t had any issues. But still, wear sunscreen!

P
patrick_dunn4/17/2026

Has anyone talked to their doctor about switching to a different combo if the side effects get too intense? I had to switch after my kidneys started acting up.