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kenneth_perez2026-04-18

I've been using Clindamycin/benzoy 1/5% Gel 35g Pmp for a few weeks now to treat my acne. It's a combination of clindamycin, an antibiotic, and benzoyl peroxide, a peeling agent, designed to kill acne-causing bacteria and clear pores. I've noticed some irritation and dryness, but overall, it seems to be working. However, the product description mentions some severe side effects that are quite concerning. I haven't experienced any of these yet, but I'm wondering if anyone else has had similar experiences. It could be very useful to know what to expect if things get worse. I've been skincare my face once a day to avoid irritation.

1 min read
last active 4/18/2026
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Comments (8)

C
carolyn_hughes4/13/2026

Be careful with this stuff—it can really dry out your skin. I had to start using a really good moisturizer to keep the irritation under control.

R
ronald_pierce4/13/2026

It's so frustrating to have to deal with medication side effects.

A
ashley_alvarez4/14/2026

I had a similar experience. I started breaking out in hives and my face was super itchy. I stopped using it immediately and spoke to my doctor, who said it was probably an allergic reaction.

H
hannah_washington4/14/2026

I'm surprised that it can cause such severe issues. I thought it was just a topical treatment.

R
ralph_andrews4/14/2026

I've had good results with this gel but have experienced some irritation. I apply a thin layer every other day and have had no severe side effects that are listed, finally started to see better results. It has been difficult to monitor my skin regarding how severe the irritation becomes.

O
olivia_quinn4/14/2026

I've been using it for a month and haven't had any issues. It's definitely helped clear my skin.

S
sean_wallace4/14/2026

I had some issues with the gel on my hairline, it caused a lot of irritation and sometimes burns. I think my skin is just sensitive!

R
russell_castro4/14/2026

I've been using Clindamycin/benzoyl 1/5% Gel for 1 year now and have had no issues with it so far. I had to go through a few trial and error products before I landed on this being the most effective medication for me and personally recommend it.

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