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judith_moreno2026-04-18

Xtampza ER 27mg Capsules have been a game-changer for managing severe pain, but as with all opioids, there are significant side effects & considerations to weigh. It's designed to be harder to abuse, but honestly, what are the real-life experiences? What are the most severe side effects to look out for? And how does it compare to other extended-release opioids? Come share your stories, tips, and warnings!

1 min read
last active 4/18/2026
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Comments (9)

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virginia_hughes4/14/2026

I've had issues with dizziness and fainting, which is scary. This can be life-threatening, so be very careful and talk to your doctor about your choices.

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stephen_sanders4/14/2026

I started taking Xtampza ER. I thought this was a safer option than other opioids. I've been on it for 2 months and I noticed some hair loss. This can't be a side effect, can it? It's been pretty devastating, I've always had thick hair.

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christine_powell4/14/2026

My wife had to switch to a different medication because she kept forgetting things. I was really shocked and worried about her. She's better now and we are both much happier.

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peter_daniels4/14/2026

I've been on Xtampza ER for about a year now, and it's made a world of difference in managing my pain. The constipation is brutal, but adjusting my diet and using stool softeners has helped. The extended-release formula is definitely a game-changer. It keeps my pain levels steady without the constant dosing. The constipation is pretty bad, but worth it for the pain relief.

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nancy_herrera4/14/2026

I experienced a really heavy allergic reaction. My skin was itchy and peeling. Luckily I stopped taking the medication immediately when I noticed it was turning into a rash.

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jonathan_hamilton4/14/2026

I have recently switched to Xtampza ER and I can swear I experienced some serotonin syndrome symptoms. I felt like I was going crazy, with agitation and seeing things that were not there. I'm sure it was just the medication. Has anyone else experienced this?

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peter_moore4/14/2026

I can't believe some of these side effects you guys are experiencing. I've been on Xtampza ER for 6 months and haven't had any issues.

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martha_fox4/14/2026

I was prescribed this for chronic back pain and I experienced some serious mood swings while on Xtampza. My doctor switched me to a different medication and that seemed to help.

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marie_ferguson4/14/2026

I’ve been on Xtampza ER for chronic pain, and it’s definitely helped, but the side effects are no joke. I have hallucinations few times a week that feel like they last mini-eternities. I am looking for some advice here.