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joyce_murray2026-04-18

I've been using Desoximetasone 0.05% Cream for my eczema for a few weeks now, and I've noticed some improvement, but I'm also experiencing some side effects. I wanted to start this thread to share my experience and hear from others who might have used this cream. What are some of your experiences with this medication? Also what are some ways you've managed side effects or any redness, swelling, or itching?

1 min read
last active 4/18/2026
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Comments (4)

J
janet_gardner4/16/2026

I had to stop using this because it burned and itched where I applied it. I had to switch to something else.

N
nicholas_schmidt4/16/2026

I’ve heard that topical steroids can sometimes cause skin thinning if used for too long. Is this a common side effect with Desoximetasone as well? Does anyone have any tips on how to monitor this? Can I use it for more than two weeks? What if I want to use it for two weeks but then stop and then use it again later, is that safe?

J
joyce_murray4/16/2026

I had to look up the side effects, I was really worried about this stuff?

A
aaron_nelson4/16/2026

Hey, just wanted to say that if you're experiencing side effects, especially the severe ones, it's crucial to talk to your doctor right away. Don't wait it out. If you're worried about the cream working or anything, a doctor can give you a different cream if you need one.