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robert_stephens2026-04-18

I started taking Epclusa 400-100mg tablets a few weeks ago for my chronic Hepatitis C. So far, it's been a mixed bag. The medication is convenient and easy to take, but I've experienced some side effects. I'm mostly feeling tired and have had a few headaches, but no nausea yet. Has anyone else dealt with this, and what can we do to mitigate the side effects? Both of my parents had Hep C and haven't dealt with it well. I really want to make sure that I can get this under control. I know the drug has been effective against all major types of Hepatitis C. I only hope my case is not the exception and most concerning, I've read about the rare but serious side effects. I don't want to experience anything life-threatening. If anyone has any tips or advice on managing these side effects, or what to do if I experience anything else, I'd really appreciate it. It's not worth all the side effects. But, has anyone else here gotten symptoms relieved after taking it? I have to call my doctor to talk about it, but I want to hear from people who have been through it already. What is the best way to do this?

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last active 2d ago
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Comments (9)

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william_webb4d ago

I'm on week 2 and feel like I have the flu. Body aches, fatigue, and a low-grade fever. Has anyone else had this? I already called the doctor.

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nina_kowalski3d ago

I'm curious about the long-term effects. Has anyone been on Epclusa for more than a year and can report how they're doing? And it has worked very well.

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peter_moore3d ago

Epclusa has been a game-changer for me. I've had minimal side effects, and my viral load is undetectable. I'm so happy I have it. I've been in the hospital for Hep C so many times. This has been something amazing. If you do experience bad side effects you can tell your doctor and he can lower your dosage and make you take it less often, but I don't think I will have to. This is the best.

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nicholas_schmidt3d ago

Epclusa saved my life. I was stage 4 liver disease and now my liver function is almost back to normal. I had a few bad side effects at first, but my doctor adjusted my other medications and things got better.

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marie_ferguson3d ago

I've been on Epclusa for 2 years now, and I've had no issues. I had a few side effects at first, but they go away after the body gets used to it. I've had no problems.

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eric_reyes3d ago

I've been on Epclusa for about 3 months now, and while I've had some tiredness and headaches, it's been manageable. I recommend taking it with food to help with any stomach upset. And make sure you stay hydrated. I can't believe it's effective against all major types of Hepatitis C. That's crazy how rare it is to be able to get rid of it. It's so good.

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hannah_alvarez3d ago

My doctor told me that the serious side effects are very rare. I stopped worrying about it and focused on getting better. I believe it's the best thing that you can do. Don't take the doctors word as gospel.

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robert_stephens3d ago

I had to stop taking it because of severe nausea. I couldn't keep any food down, and I was miserable. I wish my doctor had warned me about it. Maybe I'll have more luck with something else.

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scott_robinson3d ago

I had a mild rash that went away after a few days. It wasn't too bad and it's worth it to get rid of the Hep C. But I hope it doesn't come back.