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sean_chen2026-04-18

I recently started taking Pemrydi (Pemetrexed) for mesothelioma and am experiencing severe fatigue and nausea. I'm wondering if anyone else has had similar experiences or if there are effective remedies to manage these side effects. I'm also curious about the long-term effects of this medication and how others have coped. Thank you for your insights!

1 min read
last active 4/18/2026
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Comments (8)

A
ashley_alvarez4/15/2026

I went through this during chemo too... did NOT enjoy it. Puking in the middle of a restaurant is a unique experience.

T
timothy_thompson4/15/2026

I had a really bad allergic reaction to Pemrydi. I started breaking out in hives and had trouble breathing. I had to go to the ER, but it was scary. My oncologist switched me to a different chemotherapy drug and I'm doing much better now.

J
joyce_ford4/15/2026

I've been on Pemrydi for a few cycles now and have experienced severe flu-like symptoms, including high fever and chills. My doctor prescribed some antibiotics and it helped a bit, but it's still tough. Any other tips?

N
nancy_santos4/15/2026

This sucks. I've had a lot of nausea and mouth sores... any tips to deal with this??

L
lori_allen4/15/2026

Be sure to get plenty of rest and take it easy on yourself. You're going through a lot, and it's important to prioritize your health. Good luck, everyone!

B
beverly_spencer4/15/2026

I used to be able to eat anything. Ever since I started taking Pemrydi, my taste has completely changed. Every meal feels like it took me a thousand times longer.

J
joshua_morgan4/15/2026

I had a similar experience, but my doctor recommended some medications to manage the symptoms. Stay hydrated, eat small meals and it becomes more bearable.

R
ralph_andrews4/15/2026

I had some nerve issues with Pemrydi. I experienced numbness and tingling in my hands and feet. My doctor gave me some meds to manage it, and it's gotten a bit better. It's a tough drug, but it's supposed to work well for mesothelioma so we gotta push through.