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ruth_fox2026-04-18

I've recently been diagnosed with Wilson's disease and my doctor has prescribed Syprine (Trientine) 250mg Capsules. I've read about the potential side effects and I'm a bit nervous. I'd love to hear from anyone who has experience with this medication. How did you handle the side effects? Any tips or advice would be greatly appreciated!

1 min read
last active 4/18/2026
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Comments (5)

K
kimberly_guzman4/16/2026

I had a weird rash when I first started taking Syprine, but it went away after a few weeks. Make sure to contact your doctor if anything seems off!

K
kathleen_gray4/16/2026

I have Wilsons and I hear Trientine is the only effective drug that works. My friend has it but hates the side effects. Do you know about other drugs like zinc that can help?

K
kyle_washington4/16/2026

I've been on Syprine for a few years now. I did experience some side effects initially, like feeling very tired and weak, but my doctor adjusted the dosage and it got better. Just make sure to communicate openly with your doctor.

S
sean_wallace4/16/2026

I find that a lot of medications can make me tired, and Syprine is no exception. I just need to be better at listening to my body and taking naps when I need to.

J
joan_kennedy4/16/2026

The side effects are real, but the alternative is worse. Just think about the damage copper can do to your liver and brain. Syprine is the better choice.