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judy_berry2026-04-18

I've been struggling with severe acne and rosacea for years, and my dermatologist recently prescribed Plexion 9.8-4.8% Cream. It's been a few weeks, and I've noticed some improvement, but I'm also experiencing some side effects. I've seen a reduction in my clogged pores, but I'm dealing with some dryness and itching from this combination of sulfur and sulfacetamide. I wanted to know if anyone else has tried this cream and had similar experiences?

I'm also concerned about the more severe side effects listed in the patient information leaflet. Has anyone experienced anything like that? Any tips on how to manage the dryness and itching would be greatly appreciated.

1 min read
last active 4/18/2026
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Comments (4)

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peter_daniels4/15/2026

I've used Plexion for my seborrheic dermatitis and it helped a lot. It’s a bit drying, but a good moisturizer afterwards helps. I didn't experience any severe side effects though.

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william_webb4/15/2026

I've been using it for a month now and it's been a game-changer for my rosacea. I apply it at night and use a gentle moisturizer in the morning. No severe side effects so far, just a bit of dryness.

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ralph_andrews4/15/2026

I've been using it for a few weeks and it's been okay. The dryness is bad, though. ANY tips on how to manage it?

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logan_johnson4/15/2026

I used this for a week and it made my skin so irritated. I'm really sensitive to sulfacetamide, so I had to stop.