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aaron_nelson2026-04-17

I've been recently prescribed Otrexup 20mg/0.4ml for my rheumatoid arthritis. I'm a bit nervous about the weekly injections and the potential side effects. The doctor explained that it works by slowing down the growth of certain cells, which should help reduce inflammation, but I'm still feeling a bit anxious. I've heard about some scary side effects like allergic reactions, infections, and even bleeding issues. Has anyone else been on this medication? I'd love to hear about your experiences, tips on managing the injections, and how you handle any side effects. Also, are there any good resources or support groups out there for people on Otrexup? Any advice would be greatly appreciated!

1 min read
last active 4/17/2026
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Comments (10)

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christine_powell4/14/2026

I've been on Otrexup for about six months now, and I've had to deal with some hair loss – it's frustrating, but manageable. I've found that using a gentle shampoo and conditioner, along with a good hair mask, has helped a lot. I also started taking biotin supplements, which seemed to help. As for the injections, I found that using a numbing cream before the shot made it much easier to handle. Just apply it about 30 minutes before the injection, and you'll barely feel a thing. Also, make sure to take it easy on the day of the injection – rest and hydration are key.

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christina_kim4/14/2026

I'm really glad you're getting the help you need for your arthritis. Good luck with the medication!

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larry_gardner4/14/2026

Just started Otrexup and I am freaking out about the injection part. Any tips on how to make it less scary?

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adam_owens4/14/2026

I’m really sorry you are having to deal with this. You can take comfort in knowing that this is a common medication for your condition, so there will be plenty of support out there.

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kenneth_perez4/14/2026

I had some severe side effects when I first started, but my doctor adjusted the dosage, and it got better.

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sean_williams4/14/2026

I've been on Otrexup for about a year now, and it's been a game-changer for my rheumatoid arthritis. The injections are a bit of a pain (pun intended), but the relief they bring is totally worth it. Just make sure to stay on top of your blood tests and regular check-ups. My rheumatologist keeps a close eye on my liver and kidney functions. As for side effects, I've had some mild stomach pain and dizziness, but nothing too bad. Push through the first few weeks, and it gets easier. Also, rotating injection sites helps with any discomfort.

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lauren_meyer4/14/2026

I've been on Otrexup for a while and I've found that keeping a positive mindset really helps. It's tough, but having a support system makes all the difference. Also, consider joining an online forum for people with rheumatoid arthritis. There are a lot of helpful tips and stories out there. Plus, they have some really good information on managing side effects and dealing with the emotional toll. It's helped me a lot.

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aaron_nelson4/14/2026

Ouch, those injections sound rough. Good luck! Just remember to rotate injection sites to avoid any discomfort.

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mary_wright4/14/2026

I feel you on the anxiety. I was also nervous when I started, but I've found that keeping a journal of my symptoms and side effects has been super helpful. It's easy to forget the details when you're talking to your doctor, so having a record can make a big difference. Just remember that everyone's experience is different, so try not to get too caught up in horror stories. You got this!

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kyle_washington4/14/2026

I switched to Otrexup from another medication, and it's been a lifesaver. I had some initial side effects like fatigue and weakness, but they subsided after a few weeks. Just be patient and listen to your body. If something feels off, talk to your doctor immediately. Also, make sure to take it easy on the day of the injection – rest and hydration are key. I found that using a numbing cream before the shot made it much easier to handle. It's a game-changer.