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justin_vargas2026-04-17

I've just started taking Prempro 0.3mg/1.5mg Tabs28's to help with menopause symptoms. I'm a bit nervous about the potential side effects, especially the serious ones. I'm hoping to hear from others who have taken this medication. Did you experience any of the serious side effects like blood clots or high calcium levels? Or maybe you had some of the more common side effects like fatigue or bloating? I'm also curious about how long it took for the medication to start working and if it made a significant difference in your symptoms. Any tips or advice would be greatly appreciated! Also, I'm concerned about the potential impact on my mental health. Have any of you experienced mood changes or memory problems? Thanks in advance for sharing your experiences.

1 min read
last active 13h ago
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Comments (10)

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sean_wallace5d ago

I stopped Prempro after a few months because of the memory issues. It was just too much for me. Everyone’s different, though.

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lauren_knight5d ago

I wish I had known about the bone thinning benefits earlier. My bones feel stronger and I haven’t had any fractures.

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teresa_henry5d ago

I never had any serious side effects, but the bloating was tough. I try to eat smaller meals and stay hydrated. Good luck!

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judy_berry5d ago

I started Prempro last year and it’s been a game-changer for my hot flashes and night sweats. I did have some mood swings at first, but they leveled out after a few weeks.

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frank_vargas5d ago

I'm on my second round of Prempro. The first time, I stopped because of some weird headaches. This time, I’m taking it slow and it’s been better so far.

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peter_daniels5d ago

I had some weird skin reactions when I started. I had to switch to a different brand, but it’s all good now.

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christopher_turner5d ago

I switched to a different HRT after experiencing some depression. Everyone's different, so it might be worth keeping an eye on your mental health.

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adam_owens5d ago

I've been on Prempro for a few years now. It's helped with my hot flashes, but I did gain some weight and had some bloating. Nothing too serious though. Just take it easy and monitor your symptoms.

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nancy_santos5d ago

Be careful with this stuff. I had a friend who nearly ended up in the hospital with blood clots. Scary stuff.

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joyce_ford5d ago

My doctor warned me about the blood clot risks, so I make sure to stay active and hydrated. No issues so far, knock on wood.