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billy_cook2026-04-17

I've just started taking Carbidopa/Levodopa/Entacapone 50-200-200mg Tb for my Parkinson's and I'm hoping to hear from others who have experience with this combo. I've read about the potential side effects, but I'm curious about real-life experiences. Have any of you noticed a significant reduction in 'off' times? How have the side effects impacted your daily life? Any tips for managing them?

1 min read
last active 4/17/2026
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Comments (9)

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christopher_turner4/14/2026

This medication has been a blessing. The reduction in 'off' times has improved my quality of life significantly. Just be vigilant about the side effects and communicate with your doctor.

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ashley_alvarez4/14/2026

Has anyone tried adjusting their diet to help with the side effects? I've heard that certain foods can help mitigate some of the issues.

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amber_sherman4/14/2026

Anyone else have issues with uncontrollable urges? I started gambling more than I should have, and it was affecting my finances. Thankfully, my family noticed and we got it under control.

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marie_ferguson4/14/2026

I wish I had known about the neuroleptic malignant syndrome warning sooner. I stopped my meds abruptly and ended up in the hospital. Please, if you're taking this, talk to your doctor before making any changes.

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lauren_knight4/14/2026

I've had no major issues with this combo. Just some mild dizziness and occasional headaches. Nothing compared to the improvement in my symptoms.

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nina_kowalski4/14/2026

Anyone else get hallucinations? I started seeing things that weren't there and it was really freaking me out. My neurologist adjusted my dose and it stopped.

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joan_kim4/14/2026

I've been on this combo for about a year now, and it's been a game-changer for me. My 'off' times have reduced dramatically, but I did experience some dizziness and drowsiness at first. It's mostly subsided now.

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linda_fernandez4/14/2026

I switched to this from my previous meds and the difference is night and day. The entacapone really helps levodopa last longer. However, I did have some trouble with nausea at first. My doctor prescribed some anti-nausea meds and that helped a lot.

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christian_cox4/14/2026

Be careful with the sudden, uncontrollable sleepiness. I had an episode while driving and it was terrifying. Now I make sure to take it right before bed.