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nathan_dunn2026-04-18

I was recently hospitalized and underwent a procedure where Diprivan (Propofol) was used to help me relax. The drug worked incredibly fast, and I was out within minutes. However, I woke up feeling a bit groggy and had a cough for a while afterward. I've heard of some serious side effects and wonder if anyone else has had similar experiences or knows more about the risks? I'm curious about the long-term effects, especially since I might need more procedures in the future. I also had a bit of a reaction on my arm where it was injected, so I'm wondering if anyone else has had this happen or knows how to prevent it? Also, what are the signs of propofol infusion syndrome (PRIS) and how can it be avoided?

1 min read
last active 4/18/2026
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Comments (5)

K
kathleen_gray4/18/2026

I had a procedure where they used Diprivan but I woke up during it. I felt like I was underwater, unable to speak or move. It was scary. When they eventually woke me, I was so out of it.

J
joan_kim4/18/2026

The nurse said it's important to stay hydrated after getting Diprivan. It can affect your body's ability to regulate fluids, so drinking plenty of water can help mitigate some of the side effects.

C
christina_kim4/18/2026

Propofol infusion syndrome (PRIS) is serious stuff. I've seen it happen to a patient who was on a high dose for a long time. They had muscle pain, rapid heartbeat, and shortness of breath. It's scary.

S
sean_chen4/18/2026

PRIS is no joke. The symptoms can come on quickly and be life-threatening. It's crucial to monitor for signs like metabolic acidosis, rhabdomyolysis, hyperkalemia, and cardiac failure. If you suspect it, medical attention is needed immediately.

E
edward_gardner4/18/2026

I agree, PRIS is scary. High doses and long-term use can increase the risk, but it's still rare. Monitoring for metabolic acidosis and symptoms like muscle pain and rapid heartbeat is key.