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aaron_nelson2026-04-18

Hi everyone, I've been taking Orkambi 100-125 Tablets for the past six months, and I wanted to share my experience. Orkambi has been a game-changer for me as someone with cystic fibrosis and the F508del mutation. I've noticed a significant improvement in my lung function and overall energy levels. However, I’ve also experienced some side effects like stomach pain and diarrhea, which have been manageable. I wanted to hear from others who have been on Orkambi and their experiences, especially regarding the side effects and any tips on managing them better. Also, for those who have switched from other medications, how does Orkambi compare? Any insights would be greatly appreciated!

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last active 3d ago
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Comments (4)

A
aaron_nelson4d ago

Orkambi has been a lifesaver for me. I've had some side effects, but nothing I can't handle. It's amazing how much better I feel now compared to before. If you're considering Orkambi, I say go for it—it could be a game-changer.

L
lori_allen4d ago

My doctor suggested Orkambi, and I've been taking it for a couple of months now. I've had some minor side effects like stomach pain and headaches, but overall, it's been worth it. The improvement in my lung function has been noticeable, and I feel like I have more energy.

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william_webb4d ago

I've been on Orkambi for about a year now, and it's been a mixed bag for me. The improvement in my lung function has been noticeable, but the side effects can be tough. I've had some stomach issues and flu-like symptoms that come and go. My doctor advised me to take it with food, which has helped a bit. Has anyone else found any tricks to deal with the side effects?

J
janet_gardner4d ago

I've had some really bad side effects from Orkambi. I've been experiencing severe chest pain and shortness of breath. I'm going to talk to my doctor about it soon because this is not something I can live with. Make sure to monitor your symptoms carefully if you're on this medication.