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robert_stephens2026-04-18

I've recently been prescribed Mytesi (crofelemer) 125mg Tablets to help manage diarrhea while on antiretroviral therapy. I'm curious if anyone else here has experience with this medication. How effective has it been for you? Have you encountered any of the side effects like the common cold, cough, or gas? I'm particularly interested in hearing about any urgent side effects or allergies like rash, hives, itching, or trouble breathing. My doctor said it uses a different mechanism than other treatments by reducing water and salts in the intestines. I’m hopeful but also a bit nervous about potential reactions. Any insights or advice would be greatly appreciated!

1 min read
last active 4/18/2026
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Comments (6)

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nancy_herrera4/13/2026

If you feel weird or have any signs of a reaction, just go to the ER. Better safe than sorry, especially with HIV. I'd rather be cautious than sorry.

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elena_vargas4/13/2026

I had a slight rash a couple of weeks ago, but it was probably just a coincidence. You should always keep an eye out for anything severe and report it to your doctor. My doc also said to avoid alcohol if you're taking it, to lessen the side effects.

C
carolyn_hughes4/13/2026

I've been on Mytesi for a few months now, and it's made a huge difference. No more constant bathroom trips! However, I did experience some minor gas and a bit of a cough. Nothing too bad, though.

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william_webb4/13/2026

I feel like the side effects are worth dealing with if it means I don't have to spend my days running to the bathroom. Plus, the gas and cough aren't that bad. It’s all about perspective.

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joan_kennedy4/13/2026

Does anyone know if we can take this with other meds? I’m a bit weird about mixing meds.

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ethan_olson4/13/2026

Mytesi has been a game-changer for me. I remember when I first started taking it, I had some gas, but it went away after a week. I also had a bit of a cough for a few days, but honestly, that just seemed like a regular cold. No hiccups with the diarrhea, though. I’m just glad it’s finally under control.