Back to feed
43
401 9

Orkambi, a medication specifically designed for cystic fibrosis (CF) patients with the F508del genetic mutation, has been a game-changer for many. Containing two powerful drugs—lumacaftor and ivacaftor—Orkambi works by correcting the faulty protein in CF patients' cells. Lumacaftor helps the protein get to the right place, while ivacaftor improves its function. This combination significantly enhances lung function and overall health. However, like any medication, Orkambi comes with its share of side effects, some of which can be serious. It's crucial for patients to be aware of these potential issues and to consult their doctors if they experience any concerning symptoms. This thread is for CF patients, caregivers, and healthcare professionals to share their experiences and insights about Orkambi 150-188mg Granules.

1 min read
last active 3d ago
HOT

Comments (9)

E
edward_gardner5d ago

The liver issues are no joke. My friend had to stop taking Orkambi because of severe liver problems. If you experience any symptoms like dark urine or yellow skin, get to a doctor right away. Always listen to your body.

R
russell_castro5d ago

I've been on Orkambi for over a year now, and it's made a huge difference in my lung function. The side effects have been manageable, but it's important to stay vigilant for any serious issues. Always keep an eye on your liver and watch for signs of allergic reactions. For me, it's been worth it.

J
joan_kim4d ago

I went to my doctor first thing I noticed symptoms like nausea and headache. This drug can be overwhelming, but the benefits really do outweigh the discomfort. Stick with it, and stay on top of your symptoms.

N
nina_kowalski4d ago

Feeling tired and weak is one of the most annoying side effects for me. It’s like I’m constantly fighting fatigue on top of CF symptoms. But I guess it’s a tradeoff for the lung function improvement.

L
linda_fernandez4d ago

I've been tracking my symptoms on an app my doctor recommended and it really helps to manage what I’m experiencing. It’s also useful to show my doctor at every visit.

S
scott_sanders4d ago

For me, the flu-like symptoms were the worst. I felt like I had a constant cold. It was a tough start, but now I’m more used to it. Not sure if it's just my body adapting over time, but it's definitely better now.

S
sean_wallace4d ago

Orkambi has been a godsend for my daughter. Her lung function has improved dramatically, and she's been feeling much better overall. The side effects are mild compared to the benefits. We'll definitely stay on it.

W
william_bailey4d ago

This drug is a lifesaver, but the side effects can be tough. I've had some stomach issues, and the flu-like symptoms were no joke. But my doctor advised sticking with it, and I'm glad I did. My energy levels have improved significantly.

J
james_morrison4d ago

Can someone explain the increased sputum production? It's like my body is producing double the amount of mucus now. Anyone have any tips on how to manage it?