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hannah_alvarez2026-04-17

I've recently started taking Methotrexate 1gm/40ml Pf Single Use for my severe rheumatoid arthritis, and I'm curious to hear from others who have used this medication for various conditions. I've been warned about potential side effects, including serious ones like allergic reactions, infections, and bleeding. Has anyone else experienced these or other severe side effects? Additionally, I'd love to hear about any tips for managing milder side effects like decreased appetite or hair loss. If you're taking Methotrexate for cancer or psoriasis, what has your experience been like? Let's share our stories and support each other through this journey.

1 min read
last active 4/17/2026
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Comments (10)

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linda_fernandez4/17/2026

Methotrexate is one of the toughest medications I’ve ever taken, but it's been effective for my RA. Just make sure to stay hydrated and listen to your body. But seriously, don’t skimp on those follow ups.

C
cheryl_vazquez4/17/2026

I was really nervous about the side effects, especially the hair loss. It’s been manageable, but I’ve found that using gentle shampoo and conditioners helped a lot. It’s all part of the process, I guess.

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priya_sharma4/17/2026

Ask your doctor about getting your bloodwork done regularly. It’s important to monitor your liver and kidney function. Don’t skip the appointments, no matter how tired you feel.

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pamela_nelson4/17/2026

I take Methotrexate for my RA and the worst part is the nausea. I found that eating small, frequent meals and drinking ginger tea helped a lot. Also, I got a cool gel mattress pad to help with my achy joints while sleeping

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joan_kennedy4/17/2026

I’m only on week 2, and the side effects have been brutal. Hoping it gets better soon. Fingers crossed for all of us.

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beverly_spencer4/17/2026

I've had really weird dreams since starting this. Anyone else?

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peter_tucker4/17/2026

Just remember, everyone's experience is different. What works for one person might not work for another. Stay positive and listen to your body. You got this!

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jonathan_hamilton4/17/2026

Be careful with Methotrexate—it's serious business. I know someone who ended up in the hospital with a severe infection because they didn't recognize the symptoms quickly enough. If you feel really off, don't hesitate to call your doc.

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timothy_thompson4/17/2026

I've been on Methotrexate for my psoriasis and it's been a game-changer. The first few weeks were tough with nausea and fatigue, but my dermatologist gave me anti-nausea meds that helped a lot. The hair loss was surprising but it’s manageable. Just be patient and take it easy on yourself.

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harold_carter4/17/2026

I take Methotrexate for my cancer treatment, and the worst part is the fatigue. It's like nothing I've ever experienced. I have to take naps during the day, and I still feel so tired.