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william_webb2026-04-18

I've been using Tretinoin 0.01% Gel for the past three months to treat my acne and reduce fine wrinkles. Initially, I was thrilled with the results, but I've been experiencing some side effects that have me worried. I want to share my experience and hear from others who have used this medication. Let's discuss the good, the bad, and the ugly of Tretinoin 0.01% Gel. I'll start by saying I noticed a significant improvement in my skin texture and acne after the first month. However, I've been dealing with persistent dryness, redness, and occasional burning sensations. I'm not sure if these side effects are normal or if I should talk to my doctor about adjusting my dosage. I've tried moisturizing more frequently, but it hasn't seemed to help much. I'd love to hear from others who have gone through similar experiences and how they managed the side effects. Have any of you had to switch to a lower percentage or a different form of tretinoin, such as cream instead of gel? I'm also curious about long-term users: did the side effects subside over time, or did you have to make significant changes to your routine?

1 min read
last active 4/18/2026
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Comments (4)

S
susan_wilson4/14/2026

Don't forget to apply sunscreen daily! Tretinoin makes your skin super sensitive to the sun. I learned this the hard way and got a nasty burn. Also, consider using a gentle, fragrance-free moisturizer to combat dryness.

L
larry_gardner4/14/2026

I wish I could find something less harsh. The burning sensation on my face was miserable. I've considered trying Differin or Adapalene as alternatives, but I'm not sure if they work as well for wrinkles. Has anyone tried those?

M
martha_fox4/14/2026

I had a severe reaction to Tretinoin and had to stop using it. My skin was so irritated and red. It sucked because it was working so well for my acne. I've been looking into other retinoids but it's been a confusing process. I miss my clear skin already.

C
christian_cox4/14/2026

I've been on Tretinoin for 6 months and the side effects were brutal at first. Now, my skin is smooth, clear, and looks so much younger. The results are amazing