Ustekinumab 45mg/0.5ml Injections: My Experience, Side Effects, and Alternatives

beverly_spencer2026-04-18 255 8

1 min read

last active 1d ago

HOT

Hello everyone. I've been using Ustekinumab (Stelara) 45mg/0.5ml injections for about a year now to manage my psoriasis. At first, I was nervous about the injection process because I'm not a fan of needles, but my doctor explained it was quick and relatively painless. I can feel the difference in my skin, but I'm worried about the potential side effects. Has anyone else experienced issues like infections or allergic reactions? Also, do you know if there are any long-term side effects? Also, what are your experiences with this medication? Have you tried other treatments? I'm curious to hear about what others have tried, and what worked best. Thanks in advance!

Psoriasis

Ustekinumab

Injections

beverly_spencer2026-04-18

1 min read

last active 1d ago

HOT

Comments (8)

jean_hudson3d ago

I've been on Stelara for a few months, and while it's helped my psoriatic arthritis, I've had some nasty side effects. I had a bad bout of diarrhea and muscle pain, and I've been super tired lately. I'm super guilty of Googling symptoms at this point, and it's driving me nuts. I'm going to bring it up with my doctor this week, but it's really gotten me down. Has anyone found anything that helped with these side effects, or have any tips to minimize them?

justin_vargas3d ago

How long does it take for Stelara to start working? I just started and I'm already losing hope. Does anyone have an idea of a timeline or maybe any tricks to speed up the process? I'm really struggling with my symptoms right now.

sean_wallace3d ago

I've had pretty serious infections since starting Stelara. One time, I ended up in the hospital with pneumonia. It was awful. Make sure you tell your doctor about any signs of infection right away.

larry_gardner3d ago

I've tried a bunch of different treatments, and Stelara is the only one that's given me real relief. It's pricey, but my insurance covers most of it. If you're thinking about switching, talk to your doctor. It might be worth it.

harold_carter3d ago

I've been on Stelara for a year and a half now. It's definitely helped my Crohn's, but I've also had some weird side effects. I've had some weird skin growths and muscle aches, but nothing too bad. I'm hoping they'll go away eventually.

peter_daniels3d ago

Be careful with Stelara. I have a friend who developed PRES, and it was scary. If you start experiencing confusion, vision changes, or severe headaches, get to a doctor ASAP. It's rare, but it's serious.

judith_moreno3d ago

I don't know why I even worry about it. It's just an injection. I've had worse with my flu shots.

priya_sharma3d ago

I've had a great experience with Stelara. My psoriasis has dramatically improved, and I haven't had any major side effects. Just some mild irritation at the injection site and occasional headaches. I think it's worth it for the relief it provides.