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aaron_nelson2026-04-18

Daurismo (glasdegib) is a newly approved medication used to treat acute myeloid leukemia (AML) in older adults or those who cannot tolerate intensive chemotherapy. It works by blocking a specific pathway in cancer cells, which helps to slow down or stop the growth of the cancer. While this drug offers new hope for AML patients, it's crucial to understand the potential side effects and how they might impact treatment. This thread is for discussing the serious and other possible side effects listed for Daurismo, as well as sharing experiences and insights on managing them.

1 min read
last active 4/18/2026
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Comments (6)

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christian_cox4/14/2026

Has anyone else noticed swelling? I've had some swelling in my legs and ankles, and it's been really uncomfortable. My doctor says it's manageable with medication, but it's still a hassle. Make sure you keep an eye on this and talk to your doctor if it gets worse.

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linda_fernandez4/14/2026

I had a really bad allergic reaction to Daurismo. It was scary, but I'm glad I got to the hospital in time. If you experience any swelling or trouble breathing, go to the ER immediately. It's not worth the risk.

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peter_moore4/14/2026

I had a friend who was on this medication and had to stop due to severe electrolyte problems. It's important to monitor these symptoms closely. If you experience any mood changes, confusion, or muscle spasms, don't wait—contact your doctor right away.

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amber_sherman4/14/2026

Anyone else experiencing a change in taste? I can't enjoy my coffee anymore, and it's been a bummer! Also, mouth sores have been a real pain, but I've found that a good mouth rinse helps a lot.

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christopher_hansen4/14/2026

I've been on Daurismo for a few months now. The biggest issue for me has been the gastrointestinal symptoms. I've had bouts of diarrhea and upset stomach, but my doctor assured me it's manageable with medication and diet adjustments. I've also noticed some muscle pain, which can be pretty annoying, but it's bearable. Overall, I think the benefits outweigh the side effects, but it's important to stay in close contact with your healthcare team.

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cheryl_vazquez4/14/2026

I've actually been surprised by how few side effects I've experienced. Just some mild fatigue and a bit of a headache, but nothing too bad. Everyone's experience is different, so don't assume the worst.