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harold_carter2026-04-18

Recently diagnosed with multiple myeloma and starting Sarclisa infusions? I just had my first round and want to share some tips and info on the side effects I experienced, I would love to hear from others too!

Sarclisa targets the CD38 protein on cancer cells, essentially helping your immune system zero in on and destroy these cancerous plasma cells. My oncologist recommended it and explained that it's given as an infusion. I’ve heard the infusion reactions can be a bit rough, but the nurses at the clinic were amazing and had everything under control.

For those who have been through it, I’m curious to know what you did to manage the side effects. And if anyone has advice on handling the infusion reactions, that would be super helpful too.

The serious side effects list is pretty scary, but my doc assured me that while they can happen, they’re rare. I already had my prescription for Sarclisa 500mg/25ml, so I’m hoping to manage the side effects and avoid the serious symptoms.

1 min read
last active 4/18/2026
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Comments (7)

J
judy_berry4/16/2026

I felt so tired after my infusions, like I couldn't do anything. But my doc said it was normal in the beginning. I did get a lot better with rest and good food.

S
scott_sanders4/16/2026

I had a major reaction the first time. I didn’t think it would be that bad. Lots of chills and a rash that got red. It was scary, but the medical team had a protocol in place. SAFETY first. But it got so much better after the first time, the next rounds were so much easier!.

F
frances_pierce4/16/2026

I've been on Sarclisa for a few months now, and the infusion reactions were the worst part at first. I found that taking an antihistamine before my infusion helped a lot with the itching and rashes. Also, staying hydrated and wearing loose clothes made the experience a bit more comfortable.

J
joyce_murray4/16/2026

I find it helps to have a distraction during the infusion like watching a movie or reading a book. Makes the time pass quicker!

K
kenneth_jordan4/16/2026

I agree with the hydration tip. It's a game-changer. And don't forget to rest after your infusion. My energy levels took a hit the first few times, but now I'm better prepared.

N
nancy_herrera4/16/2026

Don’t forget to talk to your nurses and doctors about your fears and concerns. They’re there to support you and make this process as smooth as possible.

R
ronald_pierce4/16/2026

Be sure to report any unusual symptoms to your doctor right away. I had some mild skin irritation and a slight fever after my second infusion, and the doc adjusted my meds to help with that. It’s all about communication and vigilance.